The decision whether treatment is necessary depends on the needs of the patient, the recalcitrance of their disease, and the likelihood of treatments to leave pigmentary alteration or scarring. Most of the common treatments consist of various means to traumatize the lesions. The following is a brief summary of some of the more common treatments.
One of the most common, quick, efficient methods of treatment is cryotherapy. Liquid nitrogen, dry ice, or Frigiderm are applied to each individual lesion for a few seconds. Repeat treatments in 2-3-week intervals may be required. Hyper- or hypopigmentation and scarring may be caused by this treatment.
An easy method to remove the lesions is eviscerating the core with an instrument such as a scalpel, sharp tooth pick, edge of a glass slide, or any other instrument capable of removing the umbilicated core. Because of its simplicity, patients, parents, and caregivers may be taught this method so new lesions can be treated at home. This method is simple but may not be tolerated by small children.
Curettage is another method of removal. It can be used with and without light electrodessication. This method is more painful, and it is recommended that a topical anesthetic cream be applied to the lesions before the procedure to decrease the pain. This method has the advantage of providing a reliable tissue sample to confirm the diagnosis.
Another reported treatment involves the use of adhesive tape. The adhesive side of the tape is repeatedly applied to and removed from the lesion for 10-20 cycles. This action effectively removes the superficial epidermis from the top of the lesion. However, repeated use of the same strip has the potential to spread the virus to adjacent, uninvolved skin.
A 25% suspension in a tincture of benzoin or alcohol may be applied once a week. This treatment requires some precautions. It contains two mutagens, quercetin and kaempherol. Some of the listed side effects include severe erosive damage in adjacent normal skin that may cause scarring and systemic effects such as peripheral neuropathy, renal damage, adynamic ileus, leucopenia, and thrombocytopenia, especially if used generously on mucosal surfaces.
Podofilox is a safer alternative to podophyllin and may be used by the patient at home. The recommended use usually consists of application of 0.05 ml of 5% podofilox in lactate buffered ethanol twice a day for 3 days. The active agent is absolutely contraindicated in pregnancy.
Cantharidin has been used with success in the treatment of MCV. This blister-inducing agent is applied carefully and sparingly to the dome of the lesion with or without occlusion and left in place for at least 4 hours before being washed off. Cantharidin can cause severe blistering. It should be tested on individual lesions before treating large numbers of lesions. It should not be used on the face. When tolerated, this treatment is repeated every week until the lesions clear. Usually 1-3 treatments are necessary.
Besides treatments mentioned above, antiviral and immune-modulating treatments have recently been added to the options. NaturesPharma has investigated hundreds of anti-viral substances from natural sources, including both extracts and pure compounds from herbal medicines as reported in laboratory studies, as well as conducted our own independent trials.
AntiMolluscum-Rx is a powerful antiviral agent which inhibits the signal transduction pathways of molluscum viral proteins. The result is that molluscum viral cells are destroyed and eliminated from infected tissues in a relatively short time with little to no evidence of the virus appearing in conventional microscopic sections of previously infected cells.
From a chemical standpoint, the fight against molluscum is actually a battle of microparticles. The Molluscum contagiosum virus is infinitely small, and as a result, we need infinitely small naturally occurring antiviral agents to penetrate cell membranes of infected cells to attack and destroy the molluscum virus.
NaturesPharma have identified a significant number of naturally occurring small molecules, like phenolics, polyphenols, terpenes (e.g., mono-, di-, tri-), and flavonoids which have incredible antiviral action, used medicinally to eliminate molluscum, and heavily concentrated in AntiMolluscum-Rx.
A large number of sesquiterpenes concentrated in AntiMolluscum-Rx exhibit quantifiable antiviral activities against pox viruses such as molluscum. AntiMolluscum-Rx has excellent antiviral activity against hulled viruses as it causes their cellular death upon exposure. To learn the effectiveness of this treatment against molluscum, please go to http://www.naturespharma.org.